一、中文名称：AntiPEGAntibody，PEG抗体

二、产品描述

尊龙凯时的PEG（聚乙二醇）是由重复的乙二醇单元组成的复合物，具有高亲水性、无毒、无抗原性及良好的生物兼容性等优势。PEG化修饰能显著改变药物的物理化学性质，提升血浆半衰期，延长吸收时间，并还能改善药物与细胞受体的结合亲和力，从而增强肿瘤的靶向性。在PEG化修饰药物的研究中，PEG抗体是不可或缺的重要工具。抗PEG抗体可用于监测药物的药代动力学，包括分布、代谢、排泄以及聚乙二醇化蛋白质或分子（如纳米颗粒）的质量控制。尊龙凯时提供的Antibodysystem PEG系列抗体适用于ELISA、WB和HC等实验方法。

三、相关产品

• Anti-PEGAntibody(E112#)(RGK24701)
• Anti-PEGAntibody(6A9/PEG2)(RGK24702)
• Anti-PEGAntibody(14B5/PEG1a)(RGK24703)
• Anti-PEGAntibody(14B5/PEG1b)(RGK24704)
• Anti-PEGAntibody(331)(RGK24705)
• Anti-PEGAntibody(2B5)(RGK24706)
• Anti-PEGAntibody(32D6)(RGK24707)
• Anti-PEGAntibody(AGP3)(RGK24708)
• Anti-PEGAntibody(63)(RGK24709)
• Anti-PEGAntibody(15-2b)(RGK24710)

四、产品详情

产品名称：Anti-PEGAntibody(E112#)(RGK24701)
别名：PEG, Poly(ethyleneglycol), Polyethyleneglycol
货号：RGK24701
宿主：Mouse
同种型：IgG1, kappa
克隆类型：Monoclonal
靶标：PEG, Poly(ethyleneglycol), Polyethyleneglycol
浓度：1mg/ml
内毒素水平：请咨询实验室获取信息
纯度：95%（通过SDS-PAGE测定）
纯化方式：Protein A/G 从细胞培养上清中纯化
克隆号：E112#
应用：ELISA, WB
状态：液体
保存溶液：0.01M PBS, pH 7.4
稳定性和存储：使用手动解冻冰箱，避免反复冻融；短期（1-2周）存储于4°C，长期存储于-20°C可达12个月， -80°C可长期保存。

五、参考文献

以下是关于抗PEG抗体的相关文献参考：
Anti-PEG antibodies in the clinic: Current issues and beyond (PMID: 27369864)
“PEG dilemma” for liposomes and its solving approaches (PMID: 26118102)
Chemistry Routes for Copolymer Synthesis Containing PEG for Targeting, Imaging, and Drug Delivery Purposes (PMID: 31336703)
Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route (PMID: 37355210)
Exosome isolation based on polyethyleneglycol (PEG): a review (PMID: 39702782)
Quantitation of PEG on PEGylated Gold Nanoparticles Using Reversed Phase High Performance Liquid Chromatography and Charged Aerosol Detection: Version 10 (PMID: 39012983)
PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication (PMID: 25547369)
Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use (PMID: 26191379)
Free PEG Suppresses Anaphylaxis to PEGylated Nanomedicine in Swine (PMID: 38469811)
Stepwise PEG synthesis featuring deprotection and coupling in one pot (PMID: 35079293)
The Importance of Poly(ethyleneglycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation (PMID: 32024289)
Missing PEG tube found at the ileocecal valve (PMID: 34401032)
Polyethylene Glycol (PMID: 30694626)
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice (PMID: 36632951)
The uses and properties of PEG-linked proteins (PMID: 1458545)
Accelerated clearance by antibodies against methoxy PEG depends on pegylation architecture (PMID: 36641121)

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